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Introduction
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative condition of the motor neurons in the brain, brainstem and spinal cord.[1] Upper motor neuron (UMN) signs resulting from the affection of the cortical motor neurons are characterized by spasticity and hyperreflexia while lower motor neuron (LMN) signs secondary to degeneration of brainstem and spinal cord alpha motor neurons manifest as asymmetric atrophy and weakness in the bulbar region and limbs respectively.
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HP Table Reports
The global prevalence of ALS is 2 cases per 100,000 individuals, with notable spikes in countries like Italy, Japan and United States

Clinical characteristics of ALS patients
There were 28 MND patients included in the study, 50% (n = 14) of which were male. The median age was 55 years while the median duration from onset to diagnosis was 1.5 years.
Gender
Male
20120
20241
21022
21023
Female
20230
20241
21022
13423
Race
White
200
211
1022
213
Black
230
20241
222
133
Other
381
20241
204
123

This study showed that the management of MND in the Philippines is largely inadequate and further improvement in the health care system in handling rare neurologic cases must be implemented to enhance their quality of life.
Year
2020
2021
2022
2023
Total
40,350
40,482
41,144
34,446
Gender
Male
20120
20241
21022
21023
Female
20230
20241
21022
13423

Demographic and clinical data such as age, sex, age of onset of symptoms, duration from onset until confirmed diagnosis, the initial limb affected, family history, and ALSFRS-R score were recorded.
Year
2020
2021
2022
2024
Total
40,350
40,482
41,144
34,446
Gender
Male
20120
20241
21022
21023
Female
20230
20241
21022
13423
Race
Filipino
230
20241
222
133
Other
381
20241
204
123
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